CD74 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CD74 wild-type allele is located in the vicinity of 5q32 and is approximately 11 kb in length. This allele, which encodes HLA class II histocompatibility antigen gamma chain protein, is involved in MHC class II antigen processing and presentation. A translocation of this gene and the ROS1 gene may be associated with non-small cell lung cancer.

**Synonyms:** - CD74 Molecule wt Allele - CD74 Molecule, Major Histocompatibility Complex, Class II Invariant Chain Gene - DHLAG - Gamma Chain of Class II Antigens Gene - HLA-DR-Gamma Gene - HLADG - II - Ia-Associated Invariant Chain Gene - Ia-GAMMA - Ii - MHC HLA-DR Gamma Chain Gene