CBFA2T3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CBFA2T3 wild-type allele is located in the vicinity of 16q24 and is approximately 102 kb in length. This allele, which encodes protein CBFA2T3, is involved in the repression of transcription. A translocation t(16;21)(q24;q22) of this gene and the RUNX1 gene is associated with acute myeloid leukemia.

**Synonyms:** - CBFA2/RUNX1 Partner Transcriptional Co-Repressor 3 wt Allele - CBFA2/RUNX1 Translocation Partner 3 Gene - Core-Binding Factor, Runt Domain, Alpha Subunit 2; Translocated To, 3 Gene - ETO2 - MTG16 - MTG8-Related Gene 2 Gene - MTGR2 - Myeloid Translocation Gene 8 and 16b Gene - Myeloid Translocation Gene On Chromosome 16 - ZMYND4