Nucleoside Reverse Transcriptase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** A substance with a structure similar to a nucleoside molecule that is capable of occupying the active catalytic site of a reverse transcriptase resulting in inhibition of enzyme function, chain termination, and inhibition of viral replication. These compounds are converted to their active phosphorylated forms by cellular kinases.

**Synonyms:** - NRTI - Nucleoside Analog Reverse Transcriptase Inhibitor