DDX10 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DDX10 wild-type allele is located within 11q22-q23 and is approximately 276 kb in length. This allele, which encodes probable ATP-dependent RNA helicase DDX10 protein, is involved in the modulation of both ATP hydrolysis and RNA metabolism. A chromosomal inversion inv(11)(p15q22) which fuses this gene and the NUP98 gene is associated with myeloid malignancies.

**Synonyms:** - DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 10 wt Allele - DEAD-Box Helicase 10 wt Allele - DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 10 (RNA Helicase) Gene - DEAD/H-Box 10 Gene - Dbp4 - HRH-J8