ERC1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ERC1 wild-type allele is located in the vicinity of 12p13.3 and is approximately 505 kb in length. This allele, which encodes ELKS/Rab6-interacting/CAST family member 1 protein, is involved in the modulation of signaling. Both mutation of the gene and a chromosomal translocation t(10;12)(q11;p13) of this gene and the RET gene are associated with thyroid papillary carcinoma.

**Synonyms:** - CAST2 - Cast2 - ELKS - ELKS/RAB6-Interacting/CAST Family Member 1 wt Allele - FLJ31750 - KIAA1081 - MGC12974 - RAB6-Interacting Protein 2 Gene - RAB6IP2