ARHGAP26 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ARHGAP26 wild-type allele is located in the vicinity of 5q31 and is approximately 459 kb in length. This allele, which encodes Rho GTPase-activating protein 26, is involved in the modulation of signaling by both transforming protein RhoA and cell division control protein 42 homolog. Both mutation of the gene and a chromosomal translocation t(5;11)(q31;q23) of this gene and the MLL gene are associated with juvenile myelomonocytic leukemia.

**Synonyms:** - FLJ42530 - GRAF - GTPase Regulator Associated With the Focal Adhesion Kinase pp125 Gene - KIAA0621 - OPHN1L - OPHN1L1 - Rho GTPase Activating Protein 26 wt Allele