FOXP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human FOXP1 wild-type allele is located in the vicinity of 3p14.1 and is approximately 629 kb in length. This allele, which encodes forkhead box protein P1, plays a role in the negative regulation of transcription. Mutation of the gene is associated with mental retardation with language impairment and autistic features. A translocation t(9;3)(p13;p14.1) of this gene with the PAX5 gene is associated with acute lymphoblastic leukemia.

**Synonyms:** - 12CC4 - FLJ23741 - Fork Head-Related Protein Like B Gene - Forkhead Box P1 wt Allele - Glutamine-Rich Factor 1 Gene - HSPC215 - MGC12942 - MGC88572 - MGC99551 - QRF1 - hFKH1B