GATA2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GATA2 wild-type allele is located in the vicinity of 3q21.3 and is approximately 14 kb in length. This allele, which encodes endothelial transcription factor GATA-2 protein, plays a role in both transcriptional regulation and DNA binding. Mutation or aberrant expression of the gene is associated with myelodysplasic syndrome, chronic myeloid leukemia and aplastic anemia.

**Synonyms:** - DCML - FLJ45948 - GATA Binding Protein 2 wt Allele - IMD21 - MGC2306 - MONOMAC - NFE1B