HLF wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HLF wild-type allele is located in the vicinity of 17q22 and is approximately 60 kb in length. This allele, which encodes hepatic leukemia factor, plays a role in the modulation of transcription. A chromosomal translocation t(17;19)(q22;p13.3) with the TCF3 gene is associated with childhood pre-B-cell acute lymphoblastic leukemia.

**Synonyms:** - HLF Transcription Factor, PAR BZIP Family Member wt Allele - HLF, PAR BZIP Transcription Factor Gene - Hepatic Leukemia Factor Gene - MGC33822 - PAR BZIP Transcription Factor Gene