KDM5C wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KDM5C wild-type allele is located within Xp11.22-p11.21 and is approximately 34 kb in length. This allele, which encodes lysine-specific demethylase 5C protein, plays a role in both histone modification and transcriptional regulation. Mutation of the gene is associated with JARID1C-related syndromic X-linked mental retardation and may be associated with clear cell renal carcinoma.

**Synonyms:** - DXS1272E - JARID1C - Jumonji, AT Rich Interactive Domain 1C (RBP2-Like) Gene - Jumonji, AT Rich Interactive Domain 1C Gene - Lysine (K)-Specific Demethylase 5C wt Allele - MRX13 - MRXJ - MRXSCJ - MRXSJ - RP11-258C19.2 - SMCX - Selected cDNA On X, Mouse, Homolog of Gene - Smcy Homolog, X-Linked (Mouse) Gene - XE169