MN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MN1 wild-type allele is located in the vicinity of 22q12.1 and is approximately 53 kb in length. This allele, which encodes transcriptional activator MN1 protein, plays a role in tumor suppression. Mutation of the gene is associated with meningioma and a chromosomal translocation t(12;22)(p13;q11) of this gene and the ETV6 gene is associated with acute myeloid leukemia.

**Synonyms:** - CTA-437G10_B.1 - MGCR - MGCR1 - MGCR1-PEN - MN1 Proto-Oncogene, Transcriptional Regulator wt Allele - Meningioma (Disrupted In Balanced Translocation) 1 Gene - Meningioma (Translocation Balanced) Gene - Meningioma Chromosome Region 1 Gene - Meningioma Chromosome Region Gene - dJ353E16.2