MLF1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MLF1 wild-type allele is located in the vicinity of 3q25.1 and is approximately 36 kb in length. This allele, which encodes myeloid leukemia factor 1 protein, is involved in both cell cycle arrest and the regulation of transcription. A chromosomal translocation t(3;5)(q25.1;q34) of this gene and the NPM1 gene is associated with myelodysplastic syndrome.

**Synonyms:** - Myeloid Leukemia Factor 1 wt Allele