NOTCH2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NOTCH2 wild-type allele is located within 1p13-p11 and is approximately 158 kb in length. This allele, which encodes neurogenic locus notch homolog protein 2, is involved in the mediation of cell-cell signaling. Mutation of the gene is associated with both Alagille syndrome type 2 and Hajdu-Cheney syndrome.

**Synonyms:** - AGS2 - HJCYS - Notch (Drosophila) Homolog 2 Gene - Notch 2 wt Allele - Notch Homolog 2 (Drosophila) Gene - Notch Homolog 2 Gene - Notch, Drosophila, Homolog of, 2 Gene - hN2