PRDM16 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PRDM16 wild-type allele is located within 1p36.23-p33 and is approximately 369 kb in length. This allele, which encodes histone-lysine N-methyltransferase PRDM16 protein, is involved in the modulation of both fat cell differentiation and gene transcription. A reciprocal translocation t(1;3)(p36;q21) of the gene and the RPN1 gene is associated with myelodysplastic syndrome and acute myeloid leukemia.

**Synonyms:** - CMD1LL - KIAA1675 - KMT8F - LVNC8 - MDS1/EVI1-Like Gene - MDS1/EVI1-Like Gene 1 Gene - MEL1 - MGC166915 - PFM13 - PR Domain 16 Gene - PR Domain Containing 16 Gene - PR/SET Domain 16 wt Allele