ZNF384 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ZNF384 wild-type allele is located in the vicinity of 12p12 and is approximately 23 kb in length. This allele, which encodes zinc finger protein 384, plays a role in both the modulation of transcription and DNA binding. At least 3 translocations affecting this gene are associated with acute lymphoblastic leukemia. Translocation t(12;17)(p13;q11) fuses the gene to the TAF15 gene, t(12;19)(p13;p13) generates a fusion with the TCF3 gene and t(12;22)(p13;q12) fuses this gene and the EWSR1 gene.

**Synonyms:** - CAGH1 - CAGH1A - CIZ - ERDA2 - FLJ59043 - NMP4 - TNRC1 - Trinucleotide Repeat Containing 1 Gene - Zinc Finger Protein 384 wt Allele