Ponezumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A humanized monoclonal antibody (IgG2deltaA) raised against amyloid beta peptides with Alzheimer disease treatment application. Ponezumab recognizes and binds the free carboxy terminal amino acids 33-40 of the amyloid beta peptide 1-40 and may be used in a passive immunotherapy treatment.

**Synonyms:** - Anti-human beta-amyloid Monoclonal Antibody PF-04360365 - PF-04360365 - PONEZUMAB - RN-1219