Atinumab

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Pharmacologic Substance

**Definition:** A monoclonal antibody directed against reticulon-4, with immunomodulating activity. Atinumab binds to reticulon-4, stimulating neurite outgrowth, which may prevent neuronal damage or may facilitate the regeneration of damaged neurons. Reticulon-4, also called Neurite outgrowth inhibitor or Nogo, is an inhibitor of neurite outgrowth and may prevent neuronal regeneration in the central nervous system.

**Synonyms:** - 6A3-IgG4 - ATI355 - ATINUMAB - Immunoglobulin G4-Kappa, Anti-[Homo sapiens RTN4 (Reticulon 4, Neurite Outgrowth Inhibitor, NOGO), Isoform A], Homo sapiens Monoclonal Antibody