Omadacycline Tosylate

**Semantic type:** Antibiotic|Organic Chemical|Pharmacologic Substance

**Definition:** The tosylate salt form of omadacycline, an aminomethylcycline and a semisynthetic tetracycline derivative, with antimicrobial activity. Upon administration, omadacycline binds to the bacterial 30S ribosomal subunit and inhibits bacterial protein synthesis. Omadacycline is engineered to overcome certain tetracycline resistance mechanisms, including tetracycline-specific efflux pumps and ribosomal protection.

**Synonyms:** - 2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-(((2,2-dimethylpropyl)amino)methyl)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a- tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-,4-methylbenzenesulfonate (1:1) - Nuzyra - Nuzyra - OMADACYCLINE TOSYLATE - PTK 0796 - PTK-0796