TRPM7 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TRPM7 wild-type allele is located in the vicinity of 15q21 and is approximately 130 kb in length. This allele, which encodes transient receptor potential cation channel subfamily M member 7 protein, is involved in the mediation of both protein phosphorylation and ion transport. Mutation of the gene is associated with amyotrophic lateral sclerosis-parkinsonism/dementia complex type 1. A chromosomal rearrangement of this gene and the CYP19A1 gene is associated with aromatase excess syndrome.

**Synonyms:** - ALSPDC - CHAK - CHAK1 - FLJ20117 - FLJ25718 - LTRPC7 - TRP-PLIK - Transient Receptor Potential Cation Channel Subfamily M Member 7 wt Allele - Transient Receptor Potential Cation Channel, Subfamily M, Member 7 Gene - Transient Receptor Potential-Phospholipase C-Interacting Kinase Gene