GRIN2A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GRIN2A wild-type allele is located in the vicinity of 16p13.2 and is approximately 429 kb in length. This allele, which encodes glutamate receptor ionotropic, NMDA 2A protein, plays a role in both NMDA binding and ion transport. Mutations in the gene are associated with epilepsy, ovarian cancer and melanoma.

**Synonyms:** - EPND - FESD - GluN2A - Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2A wt Allele - Glutamate Receptor, Ionotropic, N-Methyl-D-Aspartate Subunit 2A Gene - LKS - NMDAR2A - NR2A