IL1RN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IL1RN wild-type allele is located in the vicinity of 2q14.2 and is approximately 27 kb in length. This allele, which encodes interleukin-1 receptor antagonist protein, plays a role in the regulation of interleukin-1-mediated signal transduction. Mutation or polymorphism of the gene is associated with susceptibility to microvascular complications of diabetes type 4, interleukin 1 receptor antagonist deficiency, increased risk of osteoporotic fractures and gastric cancer

**Synonyms:** - DIRA - ICIL-1RA - IL-1RN - IL-1ra - IL-1ra3 - IL1F3 - IL1RA - IRAP - Interleukin 1 Receptor Antagonist wt Allele - MGC10430 - MVCD4