MRE11 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MRE11 wild-type allele is located in the vicinity of 11q21 and is approximately 77 kb in length. This allele, which encodes double-strand break repair protein MRE11, is involved in the modulation of DNA recombination, telomere maintenance and double-strand break repair. Mutation of the gene is associated with ataxia telangiectasia-like disorder.

**Synonyms:** - AT-Like Disease Gene - ATLD - HNGS1 - MRE11 Homolog A, Double Strand Break Repair Nuclease Gene - MRE11 Homolog, Double Strand Break Repair Nuclease wt Allele - MRE11 Meiotic Recombination 11 Homolog A (S. cerevisiae) Gene - MRE11A - MRE11B - Meiotic Recombination (S. cerevisiae) 11 Homolog A Gene - Meiotic Recombination 11, S. cerevisiae, Homolog of, A Gene