NEUROD1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NEUROD1 wild-type allele is located in the vicinity of 2q32 and is approximately 8 kb in length. This allele, which encodes neurogenic differentiation factor 1 protein, is involved in both DNA binding and transcriptional activation. Mutation of the gene is associated with both maturity-onset diabetes of the young type 6 and type 2 diabetes mellitus.

**Synonyms:** - BETA2 - BHF-1 - BHLHA3 - Beta-Cell E-Box Transactivator 2 Gene - MODY6 - NEUROD - NIDDM - NeuroD - Neurogenic Differentiation 1 Gene - Neurogenic Helix-Loop-Helix Protein NEUROD Gene - Neuronal Differentiation 1 wt Allele - bHLHa3