EGFR NP_005219.2:p.L858M

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the amino acid residue at position 858 in the epidermal growth factor receptor protein where leucine has been replaced by methionine.

**Synonyms:** - EGFR L858M - EGFR Leu858Met - EGFR NP_005219.2:p.Leu858Met - EGFR p.L858M - EGFR p.Leu858Met - Epidermal Growth Factor Receptor L858M - NP_005219.2:p.Leu858Met - Proto-Oncogene c-ErbB-1 L858M - Receptor Tyrosine-Protein Kinase erbB-1 L858M