EGFR NP_005219.2:p.L858R

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the amino acid residue at position 858 in the epidermal growth factor receptor protein where leucine has been replaced by arginine.

**Synonyms:** - EGFR Activating Mutation L858R - EGFR Exon 21 L858R Mutation - EGFR Exon 21 Substitution Mutation L858R - EGFR L858R - EGFR Leu858Arg - EGFR NP_005219.2:p.Leu858Arg - EGFR p.L858R - EGFR p.Leu858Arg - Epidermal Growth Factor Receptor L858R - Exon 21 Leu858Arg - NP_005219.2:p.Leu858Arg - Proto-Oncogene c-ErbB-1 L858R - Receptor Tyrosine-Protein Kinase erbB-1 L858R