Thalidomide Embryopathy Syndrome

**Semantic type:** Congenital Abnormality

**Definition:** Fetal embryopathy associated with maternal thalidomide use during pregnancy characterized by phocomelia of one or all limbs, other limb defects such as thumb abnormalities, and other structural anomalies that may include facial hemangioma, esophageal and duodenal atresia, tetralogy of Fallot, renal agenesis, and anomalies of the external ear. Long term complications may include Moebius syndrome or autism.

**Synonyms:** - Fetal Thalidomide Syndrome - Fetal Thalidomide Syndrome - Thalidomide Embryopathy - Thalidomide Embryopathy - Thalidomide-Induced Birth Defect