APOA1/APOC3 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from an inversion involving the q arm of chromosome 11 that fuses the fourth exon of the APOA1 gene with the first intron of the APOC3 gene. This fusion is associated with combined apoA-I and apoC-III deficiency. The transcripts from this fusion gene do not produce functional apolipoproteins.

**Synonyms:** - APOA1-APOC3 Fusion Gene - APOA1::APOC3 Fusion Gene