EWSR1/ATF1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(12;22)(q13;q12) which fuses the first 7 or 8 exons of the EWSR1 gene on the 5' side of exon 4 or 5 of the ATF1 gene. This rearrangement is associated with both malignant clear cell sarcoma of the soft tissue and angiomatoid fibrous histiocytoma.

**Synonyms:** - ATF1-EWSR1 Fusion Gene - ATF1/EWS Fusion Gene - EWS-ATF1 Fusion Gene - EWS/ATF1 Fusion Gene - EWSR1-ATF1 - EWSR1-ATF1 Fusion Gene - EWSR1::ATF1 Fusion Gene