EWSR1/CREB1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(2;22)(q34;q12) which fuses the first 7 exons of the EWSR1 gene to the 5' side of exon 7 of the CREB1 gene. This rearrangement is associated with angiomatoid fibrous histiocytoma and rare cases of malignant clear cell sarcoma of the soft tissue.

**Synonyms:** - EWS-CREB1 Fusion Gene - EWS/CREB1 Fusion Gene - EWSR1-CREB1 - EWSR1-CREB1 Fusion Gene - EWSR1::CREB1 Fusion Gene