TCF3/PBX1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(1;19)(q23;p13) which fuses intron 13 of the TCF3 gene with exon 2 of the PBX1 gene. This rearrangement is associated with pre-B cell acute lymphoblastic leukemia.

**Synonyms:** - E2A-PBX1 Fusion Gene - E2A-PBX1 Fusion Mutation - E2A-PBX1 Translocation Mutation - E2A/PBX1 Fusion Gene - PBX1/E2A Fusion Gene - TCF3-PBX1 Fusion Gene - TCF3::PBX1 Fusion Gene