RUNX1/RUNX1T1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene (~4.3 kb) that results from a chromosomal translocation t(8;21)(q22;q22) which fuses the first 5 exons of the RUNX1 gene to exon 2 of the RUNX1T1 gene. This rearrangement is associated with acute myeloid leukemia.

**Synonyms:** - AML-ETO Fusion Gene - AML/ETO Fusion Gene - AML1-ETO - AML1-MTG8 - AML1/ETO Fusion Gene - AML1/MTG8 - ETO/AML Fusion Gene - RUNX1-RUNX1T1 Fusion Gene - RUNX1::RUNX1T1 Fusion Gene