MLL/AFF1 Fusion Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein (~2250 aa, ~240 kDa) encoded by the MLL/AFF1 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to the C-terminal half of the AF4/FMR2 family member 1 protein.

**Synonyms:** - Histone-Lysine N-Methyltransferase MLL/AF4/FMR2 Family Member 1 Fusion Protein - KMT2A-AFF1 Fusion Protein - KMT2A::AFF1 Fusion Protein - MLL-AF4 Fusion Protein - MLL-AFF1 Fusion Protein - MLL-MLLT2 Fusion Protein - MLL/AF4 Fusion Protein - MLL/MLLT2 Fusion Protein - MLL::AFF1 Fusion Protein