MLL/GPHN Fusion Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein encoded by the MLL/GPHN fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused with the C-terminus of the gephyrin protein including the presumed tubulin-binding site and a domain homologous to the E. coli molybdenum cofactor biosynthesis protein.

**Synonyms:** - Histone-Lysine N-Methyltransferase MLL/Gephyrin Fusion Protein - KMT2A::GPHN Fusion Protein - MLL-GPH Fusion Protein - MLL-GPHN Fusion Protein - MLL/GPH Fusion Protein - MLL::GPHN Fusion Protein