World Of Taxonomy
C99339Level 4

MLL/ABI1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(10;11)(p11.2;q23) which fuses either exon 6 or 7 of the MLL gene to nucleotide 433 of the ABI1 gene. This rearrangement is associated with acute monoblastic leukemia, acute myelomonocytic leukemia and acute myeloid leukemia

**Synonyms:** - ABI1/MLL Fusion Gene - KMT2A::ABI1 Fusion Gene - MLL-ABI1 Fusion Gene - MLL::ABI1 Fusion Gene

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