MLL/AFF3 Fusion Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein encoded by the MLL/AFF3 fusion gene. This protein is comprised of the N-terminal half of the histone-lysine N-methyltransferase MLL protein, including the AT hook DNA binding domain and the DNA methyltransferase domain, fused to the C-terminal half of the AF4/FMR2 family member 3 protein.

**Synonyms:** - Histone-Lysine N-Methyltransferase MLL/AF4/FMR2 Family Member 3 Fusion Protein - KMT2A::AFF3 Fusion Protein - MLL-AFF3 Fusion Protein - MLL-LAF4 Fusion Protein - MLL/LAF4 Fusion Protein - MLL::AFF3 Fusion Protein