MLL/CASC5 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(11;15)(q23;q14) which fuses exon 8 or exon 9 of the MLL gene and exon 10 or exon 12 of the CASC5 gene. This rearrangement may be associated with acute myeloid leukemia and acute lymphoblastic leukemia.

**Synonyms:** - AF15Q14/ALL1 Fusion Gene - ALL1-AF15q14 Fusion Gene - KMT2A-KNL1 Fusion Gene - KMT2A/KNL1 Fusion Gene - KMT2A::KNL1 Fusion Gene - MLL-AF15q14 Fusion Gene - MLL-CASC5 Fusion Gene - MLL/AF15q14 Fusion Gene - MLL/D40 Fusion Gene - MLL::CASC5 Fusion Gene