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C99371Level 3

ZBTB16/RARA Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(11;17)(q23;q21) which fuses the 5' portion of the ZBTB16 gene to exon 4 of the RARA gene. This rearrangement is associated with acute promyelocytic leukemia.

**Synonyms:** - PLZF-RAR-alpha Fusion Gene - PLZF-RARA Fusion Gene - PLZF-RARalpha Fusion Gene - PLZF/RARA Fusion Gene - ZBTB16-RARA Fusion Gene - ZBTB16::RARA Fusion Gene

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