NUP98/DDX10 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal inversion inv(11)(p15q22) which fuses the first half of the NUP98 gene to the 3' portion of the DDX10 gene. This fusion is associated with both with de novo and therapy-related acute myeloid leukemia and myelodysplastic syndrome.

**Synonyms:** - NUP98-DDX10 Fusion Gene - NUP98::DDX10 Fusion Gene