World Of Taxonomy
C99582Level 3

IKZF1/BCL6 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(3;7)(q27;p12) which fuses the promoter of the IKZF1 gene near the 5' end of the BCL6 gene. This rearrangement is associated with aberrant expression of the BCL6 gene product and B-cell non-Hodgkin lymphoma.

**Synonyms:** - BCL6/IKAROS Fusion Gene - IKAROS-BCL6 Fusion Gene - IKAROS/BCL6 Fusion Gene - IKZF1-BCL6 Fusion Gene - IKZF1::BCL6 Fusion Gene

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