RARA/PML Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(15;17)(q22;q21) which fuses the first 2 exons of the RARA gene with the last six exons of the PML gene. A transcript of this gene fusion is associated with acute promyelocytic leukemia.

**Synonyms:** - RARA-PML Fusion Gene - RARA::PML Fusion Gene