RBM15/MKL1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(1;22)(p13;q13) which fuses the 5' portion of the RBM15 gene to the 3' portion of the MKL1 gene. This rearrangement is associated with infantile acute megakaryoblastic leukemia.

**Synonyms:** - OTT-MAL Fusion Gene - OTT/MAL Fusion Gene - RBM15-MKL1 Fusion Gene - RBM15-MRTFA Fusion Gene - RBM15/MRTFA Fusion Gene - RBM15::MKL1 Fusion Gene - RBM15::MRTFA Fusion Gene