EML4/ALK Fusion Protein Variant 3a

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein (785 aa, ~86 kDa) that is encoded by the EML4/ALK variant 3a fusion gene. This protein contains the amino acids encoded by exons 1-6a of the echinoderm microtubule-associated protein-like 4 and the entire cytoplasmic region of the ALK tyrosine kinase receptor protein including the tyrosine kinase domain.

**Synonyms:** - EML4-ALK Fusion Protein Variant 3a - EML4::ALK Fusion Protein Variant 3a - Echinoderm Microtubule-Associated Protein-Like 4/ALK Tyrosine Kinase Receptor Fusion Protein Variant 3a - Fusion Protein EML4-ALK Variant 3 Splicing Isoform a