EML4/ALK Fusion Protein Variant 3b

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein (796 aa, ~88 kDa) that is encoded by the EML4/ALK variant 3b fusion gene. This protein contains the amino acids encoded by exons 1-6b of the echinoderm microtubule-associated protein-like 4 and the entire cytoplasmic region of the ALK tyrosine kinase receptor protein including the tyrosine kinase domain.

**Synonyms:** - EML4-ALK Fusion Protein Variant 3b - EML4::ALK Fusion Protein Variant 3b - Echinoderm Microtubule-Associated Protein-Like 4/ALK Tyrosine Kinase Receptor Fusion Protein Variant 3b - Fusion Protein EML4-ALK Variant 3 Splicing Isoform b