EML4/ALK Fusion Protein Variant 5a

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein (630 aa, ~70 kDa) that is encoded by the EML4/ALK variant 5a fusion gene. This protein is comprised of the extreme N-terminus of the echinoderm microtubule-associated protein-like 4 fused to the entire cytoplasmic domain of the ALK tyrosine kinase receptor protein including the tyrosine kinase domain.

**Synonyms:** - EML4-ALK Fusion Protein Variant 5a - EML4::ALK Fusion Protein Variant 5a - Echinoderm Microtubule-Associated Protein-Like 4/ALK Tyrosine Kinase Receptor Fusion Protein Variant 5a - Fusion Protein EML4-ALK Variant 5 Splicing Isoform a