EML4/ALK Fusion Protein Variant 5b

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein (671 aa, ~74 kDa) that is encoded by the EML4/ALK variant 5b fusion gene. This protein is comprised of the N-terminal half of the echinoderm microtubule-associated protein-like 4 fused to the entire cytoplasmic domain of the ALK tyrosine kinase receptor protein including the tyrosine kinase domain.

**Synonyms:** - EML4-ALK Fusion Protein Variant 5b - EML4::ALK Fusion Protein Variant 5b - Echinoderm Microtubule-Associated Protein-Like 4/ALK Tyrosine Kinase Receptor Fusion Protein Variant 5b - Fusion Protein EML4-ALK Variant 5 Splicing Isoform b