Liposome-encapsulated Recombinant Human Cu/Zn Superoxide-dismutase

**Semantic type:** Pharmacologic Substance

**Definition:** A topical hydrophilic gel containing a recombinant form of the human Cu/Zn superoxide dismutase (SOD1), a cytoplasmic antioxidant enzyme, encapsulated in liposomes with potential anti-inflammatory and adjuvant activities. Upon application of liposome-encapsulated recombinant human Cu/Zn SOD as a thin film on the irradiated area, the recombinant SOD1 is released and scavenges free oxygen radicals, thereby protecting cells from oxidative stress. This may prevent radiation-induced dermatitis as well as other types of skin reactions.

**Synonyms:** - APN 201 - Liposome-encapsulated Recombinant Human Cu/Zn SOD - Lipoxysan