SPECC1/PDGFRB Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(5;17)(q33;p11.2) which fuses the 5' portion of the SPECC1 gene to the 3' portion of the PDGFRB gene. This rearrangement is associated with juvenile myelomonocytic leukemia.

**Synonyms:** - CYTSB/PDGFRB Fusion Gene - HCMOGT-1-PDGFRB Fusion Gene - HCMOGT-1/PDGFRB Fusion Gene - HCMOGT/PDGFRB Fusion Gene - HCMOGT1/PDGFRB Fusion Gene - SPECC1-PDGFRB Fusion Gene - SPECC1::PDGFRB Fusion Gene