PRKAR1A/RET Fusion Protein

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein encoded by the PRKAR1A/RET fusion gene. This protein is comprised of approximately 240 N-terminal amino acids of the cAMP-dependent protein kinase type I-alpha regulatory subunit protein, including a dimerization domain, fused with most of the C-terminal cytoplasmic domain of the proto-oncogene tyrosine-protein kinase receptor Ret protein, including the tyrosine kinase domain.

**Synonyms:** - PRKAR1A-RET Fusion Protein - PRKAR1A::RET Fusion Protein - PTC2 Chimeric Oncoprotein - PTC2-RET Fusion Protein - R1alpha/ret Fusion Protein - RIA-RET Fusion Protein - RIA/RET Fusion Protein - cAMP-Dependent Protein Kinase Type I-Alpha Regulatory Subunit/Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret Fusion Protein - ret/PTC2 Oncoprotein