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C99871Level 4

CARS/ALK Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(2;11)(p23;p15) which fuses most of the CARS gene with the last ten exons of the ALK gene. This fusion is associated with both inflammatory myofibroblastic tumors and anaplastic large cell lymphoma.

**Synonyms:** - ALK/CARS Fusion Gene - CARS-ALK Fusion Gene - CARS1::ALK Fusion Gene - CARS::ALK Fusion Gene

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