World Of Taxonomy
C99875Level 3

BIRC3/MALT1 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(11;18)(q21;q21) which fuses the 5' portion of the BIRC3 gene to the 3' portion of the MALT1 gene. This rearrangement is associated with extra-nodal presentation of marginal zone B-cell lymphoma.

**Synonyms:** - API2-MALT1 Fusion Gene - API2-MLT Fusion Gene - API2/MALT1 Fusion Gene - API2/MLT Fusion Gene - BIRC3-MALT1 Fusion - BIRC3::MALT1 Fusion Gene - MALT1/API2 Fusion Gene

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